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COE

  • Project Name National Facility for the Scientific manufacturing of Ayurvedic and Siddha Rasa Aushadies and Bhasmas
    Funding Agency Ministry of AYUSH (Under AYUSH Scheme of Centre of Excellence) Ministry of Health and Family Welfare, New Delhi
    Sanction No. and Date Z 15015/1/2010-COE dated 11th June 2010
  • Ayurveda Formulations - Candraprabha vati, Tribhuvanakirti rasa, Karpuradi Curna, Navayasa Curna, Vaisvanara Curna, Sarasvatha Curna, Kalyana Ksara, Anandabhairava Rasa, Brhat Vatachinthamani rasa, Svasananda Gutika, Vatavidhvamsana rasa, Smritisagara rasa, Kasturi matralu, Lasunadi vati and Kantavallabha rasa

    Siddha Formulations - Ayakaantha Centuram, Padigalinga Centuram, Chanda Maarutha Centuram, Padigara Parpam and Sangu Parpam

    • Affymetrix Microarray System (M/s. Imperial Life Sciences (P) Ltd)
    • Zeta sizer (Nano-ZS, Malvern Instruments, UK)
    • Phase contrast microscope with fluorescence (AxioScope. A1, Carl Zeiss, Germany)
    • Laminar flow chamber (NU-437-400S Labgard, Nuaire, USA)
    • Rotary flash vacuum evaporator (Alpha 2-4 LD, Martin Christ, Germany)
    • 2D electrophoresis (IEF100, Hoefer, USA)
    • Double beam UV-Vis spectrophotometer (ND-2000, Thermoelectron Scientific Instruments, USA)
    • QSAR Software (Schrodinger, Germany)
    • Water Purification System (M/s. Evoqua Water Technologies, Singapore)
    • Refrigerated centrifuge (5810 R, Eppendorf, Germany)
    • Voltage stabilizers
    • Completed Physico-chemical characterization of 20 formulations (15 Ayurveda and 5 Siddha) that revealed the inorganic constituents in the samples.
    • In vivo studies to evaluate the safety of Candraprabha Vati and Tribhuvanakirti Rasa preparations in male and female Wistar rats administered with repeated doses for 28 days was carried out which revealed no significant adverse effects of both formulations in the therapeutic doses.
    • Microarray analysis of animals administered with Candraprabha Vati has been performed for the first time
    • Microarray data analysis has revealed several molecular targets that might be responsible for the therapeutic effects of CPV
      • miR-434: may play a role in the anti-diabetic and anti-inflammatory activities of CPV
      • MeOX1 and Upf3b: may contribute to the rejuvenative properties of CPV
      • Osbpl7: may be involved in the therapeutic effect of CPV in hepatic disorders
      • miR877: may have a role in CPV’s therapeutic effect against fibrosis and associated complications
      • Hbaa2: may contribute to the anti-anemic effect of CPV
      • miRlet7e: may play a role in the anti-inflammatory property of CPV
    • Microarray data also revealed a gender-specific regulation of the genes with the female animals showing a marked alteration in Rab3d gene that may have a role in anti-carcinogenic property of CPV when compared male animals
    • 6 research publications emerged out of the COE project – 4 publications under 1st installment and 2 publications under 2nd installment

    Training Programmes

    • Six days training programme on "Characterization techniques in the Standardization of Herbo-Metallic Preparations" was organized from 27th April to 02nd May 2015
    • Three days training programme on "Characterization techniques in the Standardization of Herbo-Metallic Preparations" was organized from 28th to 30th March 2016

    Seminars/Conferences organized

    • An International Conference, "Phytocongress" was organized on March 7 & 8, 2013 with participation of over 200 delegates
    • An International Conference, Phytocongress 2016 - "Indian Traditional Medicine - A Conglomeration of Ancient Knowledge and Modern Science" was organized on July 21 & 22, 2016 with participation of over 200 delegates
  • 1st installment - Publications

    • Preparation and Characterization of Kowsigar kuzhambhu, a Siddha Formulation.International Journal of Pharmacy and Pharmaceutical Sciences, Subash Chandra Bose A, Brindha Pemiah, Sridharan Krishnaswamy, Uma Maheswari Krishnan, Swaminathan Sethuraman, Rajan K Sekar, 2012, Vol 4(2), pp: 65-68.
    • Unraveling ancient medicinal formulation secrets: Preparation of Gandhaga parpam. International Journal of Pharmacy and Pharmaceuical Sciences, Grace Subha Nesapriya J, Rajalakshmi Perumal, Brindha Pemiah, Sridharan Krishnaswamy, Uma Maheswari Krishnan, Swaminathan Sethuraman, Rajan K Sekar, 2012, Vol 4(2), pp: 60-64.
    • Preparation and Characterization of Chandraprabha vati, an Ayurvedic Formulation. International Journal of Pharmacy and Pharmaceuical Sciences, Safiullah A, Devanathan Rengarajan, Brindha Pemiah, Sridharan Krishnaswamy, Uma Maheswari Krishnan, Swaminathan Sethuraman, Rajan K Sekar, 2012, Vol 4(2), pp: 55-59.
    • Preparation and Characterization of Vanga bhasma, a Tin based herbo-metallic preparation. International Journal of Pharmacy and Pharmaceuical Sciences, Sushil Kumar Vishwakarma, Rajalakshmi Perumal, Brindha Pemiah, Sridharan Krishnaswamy, Uma Maheswari Krishnan, Swaminathan Sethuraman, Rajan K Sekar, 2012, Vol 4(2), pp: 49-54.

    2nd installment - Publications

    • Transcriptional Regulation of the Pregnane-X Receptor by the Ayurvedic Formulation Chandraprabha vati, RSC Advances, Stalin Selvaraj, Ramya Ramanathan , Varshini Vasudevaraja , Kalpoondi Sekar Rajan, Sridharan Krishnaswamy, Brindha Pemiah, Swaminathan Sethuraman, Vigneshwar Ramakrishnan and Uma Maheswari Krishnan, 2014, Issue 110, pp: 64967-64976. (IF: 3.119)
    • Microarray analysis of genes from animals treated with a traditional formulation Chandraprabha vati reveals its therapeutic targets, Journal of Traditional and Complementary Medicine, January 2020; Pg 36-44. (IF: 3.080)
  • Training programme 2015

    The Centre for Advanced Research in Indian System of Medicine (CARISM), SASTRA University, organized a training program for six days on "Characterization techniques in the Standardization of Herbo-metallic preparations" under the Centre of Excellence Scheme sponsored by the Department of AYUSH, Government of India, New Delhi from 27.04.2015 to 02.05.2015. The training program was inaugurated by Dr. K. Uma Maheswari, Associate Dean, SCBT, SASTRA. The details of the lecture and practical sessions of the training program are given below:

    DATE   TOPIC RESOURCE PERSON

     

     

     

    27.04.2015

    10.00am – 11.00 am

    11.30 am – 12.30 pm

     

    2.00 pm – 3.00 pm

     

    3.30 pm – 4.30 pm 

    Surface characterization Techniques

    Dr. K. Uma Maheswari

    Surface characterization Techniques

    Dr. K. S. Rajan

    Laboratory session on Material characterization (XRF,TEM, SEM &                                 TG/DTA)

    Mrs. K. L. Niraimathi, Mr. K. Balaji, Mr. Sathiyamoorthi and Dr. R. Geethasudheer

    Laboratory session on Material characterization (XRF, TEM, SEM & CHNS)

    Mrs. K. L. Niraimathi, Mr. K. Balaji, Mr. Sathiyamoorthi and Mr. R. Narendran             

     

     

     

     

    28.04.2015

    9.30 am – 10.30 am

     

    11.00 am – 12.00 pm

     

    12.00 pm – 1.00 pm

     

    2.00 pm – 3.00 pm

     

    3.30 pm – 4.30 pm

    Advanced Spectroscopic Techniques (XPS & ICPMS)

    Dr. P. Meera

    Advanced Spectroscopic Techniques (LC-MS/MS, GCMS  UV CHN)

    Dr. S. Arvind

    Advanced Spectroscopic Techniques (LC-MS/MS, GCMS  UV CHN)

    Dr. S. Selva Ganesan

    Laboratory session on Advanced Spectroscopic Techniques

    Dr. S. Sriram, Mrs. V. Sudha and Ms. R. Lavanya

    Laboratory session on Advanced Spectroscopic Techniques

    Mr. R. Narendran

     

     

    29.04.2015

    9.30 am – 10.30 am

     

    11.00 am – 12.00 pm

     

    2.00 pm – 3.00 pm

     

    3.30 pm – 4.30 pm            

    Chromatographic Techniques & Ayush parameters (TLC, HPTLC)

    Dr. S. Arvind

    Heavy Metals & Particle Sizer Analysis (AAS, Zetasizer &PSA)

    Dr. S. Selva Ganesan

    Laboratory session on Chromatographic Techniques & Ayush Parameters                                    

    Mrs. K. L. Niraimathi, Ms. R. Lavanya and Mrs. V. Sudha

    Laboratory session on Heavy Metals & Particle Sizer Analysis

    Mr. R. Narendran and Dr. R. Geethasudheer

     

     

    30.04.2015

    9.30 am – 10.30 am
    11.00 am – 12.00 pm

    12.00 pm – 1.00 pm

     

    2.00 pm – 3.00 pm
    3.30pm – 5.30 pm

    Botanical Characterization                               

    Dr. P. Brindha

    Botanical Characterization                               

    Dr. N. Ravichandran

    Phytochemical Molecules in the Identification of Plant Drugs

    Dr. V. Vadivel

    Laboratory Session on Botanical Characterization                               

    Dr. N. Ravichandran/Dr. V. Vadivel

    Visiting Herbal Garden at Thatchankurichi

    Dr. N. Ravichandran/ Dr. V. Vadivel/Dr.C.Savariraj Sahayam/ Dr. P. Rajalakshmi

    01.05.2015

    9.30 am – 10.30 am
    11.00 am – 12.00 pm

    12.00 pm – 1.00 pm

     

    2.00 pm – 3.00 pm

    3.30 pm – 4.30 pm

    In vitro Assays                                     

    Dr. Gino. A. Kurian

    In vitro Assays                                     

    Dr. V. Vadivel      

    Bioengineering Experiments in Medicinal Plants

    Dr. Bindu simon    

    Laboratory Session on In vitro Assays                                     

    Mr. R. Sriram

    Laboratory Session on In vitro Assays

    Dr. V. Vadivel

    02.05.2015

    9.30 am – 10.30 am

    11.00 am – 12.00 pm

     

    12.00 pm-1.00 pm

     

    In vivo Studies in Standardization

    Dr. S. Panchapakesan

    Biochemical Evaluations in the Herbal Drug Standardization

    Dr. S. Sriram

    Need for Histopathological Studies in determining toxicity of metallic preparations

    Dr. P. C. Prabhu

     

    2.00 pm – 3.30 pm

    Animal House Visit

     

     

    4.00pm – 4.30 pm

    Valedictory Function

     

    20 participants from various Ayurveda and Siddha Institutes in Chennai, Puducherry, Palayamkottai and Erode attended the training program. The participants in their feedback mentioned that the six days training program was a great learning experience and also requested this program to be conducted every year.

     

    List of participants - Ayush Training Programme 2015

     

    S. No Name of the Participants Name of the Institution

    1

    M. Visvanath

    SKM, Erode

    2

    S. Merish

    Government Siddha Medical College, Palayamkottai

    3

    Dr. G. Kusuma

    CSMRIADD, Chennai

    4

    Dr. B. Vijayakumar

    Vel Tech High Tech Dr. RR, Dr. SR Engineering College

    5

    Dr. S. Murugesan

    National Institute of Siddha, Chennai

    6

    Dr. S. Sivakumar

    National Institute of Siddha, Chennai

    7

    Dr. A. Manokaran

    Government Siddha Medical College, Palayamkottai

    8

    Dr. Dheenathayalan

    A.T.S.V.S Siddha Medical College,

    9

    Dr. Bharathajothi

    Tamil Univesity, Thanjavur

    10

    Dr. A. Siva Prabha

    Ayurvedic Physician, Nagercoil

    11

    Dr. V. Vijaya Kumar

    Siddha Regional Research Institute, Puducherry

    12

    Dr. P. Rajalakshmi

    SASTRA

    13

    Dr. C. Savariraj Sahayam

    SASTRA

    14

    Dr. S. Sriram

    SASTRA

    15

    Dr. M. Nijavizhi

    National Institute of Siddha, Chennai

    16

    Dr. V. C. Jijimol

    National Institute of Siddha, Chennai

    17

    Dr. S. Elamaran

     Siddha Practitioner, Aranthangi  

    18

    K. Abirami

    SASTRA

    19

    Ms. S. T. Parimala Devi

    SASTRA

    20

    Mr. Narayanaswamy

    SASTRA

    Training programme 2016

    The Centre for Advanced Research in Indian System of Medicine (CARISM), SASTRA University, organized a Training program for three days on “Characterization Techniques in the Standardization of Ayurveda and Siddha Herbo-Metallic Preparations” under the Centre of Excellence Scheme sponsored by the Department of AYUSH, Government of India, New Delhi from 28.03.2016 to 30.03.2016. The training program was inaugurated by Dr. K. Ravi, Joint Adviser, (Siddha), Ministry of Ayush, New Delhi. The details of the lecture and practical sessions of the training program are given below:

    DATE   TOPIC RESOURCE PERSON

     

     

     

    28.03.2016

    9.20 am - 10.00 am   
    10.00am – 10.45 am 
    11.30am – 12.30 pm  

     

    2.00 pm – 3.00 pm

     

    3.30 pm – 4.30 pm      

     

    Inaugural Address

    Dr. K. Ravi

    Special Address

    Dr. K. S. Rajan

    Surface Characterization Techniques

    Dr. K. Uma Maheswari

    Laboratory session on Material characterization
    (XRF, SEM, Zeta sizer & TG/DTA)

    Mrs. K. L. Niraimathi, Mr. Sathiyamoorthi and
    Dr. R. Geethasudheer

    Laboratory session on Material characterization (XRF, SEM & CHN)

    Mrs. K. L. Niraimathi, Mr. Sathiyamoorthi and Mr. R. Narendran             

     

     

    29.03.2016

    9.30 am – 10.30 am

    11.00am – 12.00 pm  
    12.00 pm – 1.00 pm
    2.00 pm – 3.00 pm

     

    3.30 pm – 4.30 pm

    Botanical Characterization                              

    Dr. N. Ravichandran

    In vitro Assays                                     

    Dr. V. Vadivel

    In vitro Assays                                     

    Dr. Gino. A. Kurian

    Laboratory session on Advanced Spectroscopic Techniques

    Dr. S. Sriram, Mrs. V. Sudha and Ms. R. Lavanya

    Biochemical Evaluations in the Herbal Drug 
    Standardization

    Dr. S. Sriram

    30.03.2016

    9.30 am – 10.30 am

     

    11.00 am – 12.00 pm

     

    12.00 pm – 1.00 pm        

    In vivo Studies in Standardization

    Dr. S. Panchapakesan

    Need for Histopathological Studies in determining toxicity 
    of metallic preparations

    Dr. P. C. Prabhu

    Pharmacological screening methods

    Dr. C. David Raj

    2.00pm – 4.00pm

    Animal House Visit

     

    53 participants from various Ayurveda and Siddha Institutes in Chennai, Cuddalore, Madurai, Coimbatore, Kanchipuram, Palayamkottai and Bangalore attended the training program. The participants said that the program was very beneficial to them as it offered valuable theoretical and technical inputs on the role of modern characterization techniques in the standardization of herbo-metallic preparations.

     

    List of Participants from AYUSH fraternity in Training Programme 2016

    Date Name of the Participants Researchers from Department of AYUSH Institution  

    28th to 30th March 2016

    Dr. S. Vanathi

    Student  (MD)

    National Institute of Siddha, Chennai

    Dr. K. Vijayalakshmi

    Student  (MD)

    National Institute of Siddha, Chennai

    Dr. S. Manonmani

    Student  (MD)

    National Institute of Siddha

    Dr. G. SumaiyaJabeen

    Student  (MD)

    National Institute of Siddha

    Dr. Vinayak. S. Nair

    Student  (MD)

    National Institute of Siddha

    Dr. V. R. Dinesh

    Student  (MD)

    National Institute of Siddha

    Dr. S. KarthikNagarajan

    Student  (MD)

    National Institute of Siddha

     

    Dr. P. Saranya

    Student  (MD)

    National Institute of Siddha

     

    Dr. S. Aishwarya

    Student  (MD)

    National Institute of Siddha

     

    Dr. S. Savitha

    Student  (MD)

    National Institute of Siddha

     

    Dr. R. Vinodini

    Student  (MD)

    National Institute of Siddha

     

    Dr. M. Lavanya

    Student  (MD)

    National Institute of Siddha

     

    Dr. J. Kanimozhi

    Student  (MD)

    National Institute of Siddha

     

    Dr. A. M. Dharshana

    Student  (MD)

    National Institute of Siddha

     

    Dr. C. Parkavi

    Student  (MD)

    National Institute of Siddha

     

    Dr. S. P. Rajalakshmi

    Student  (MD)

    National Institute of Siddha

     

    Dr. V. M. Karthick

    Student  (MD)

    National Institute of Siddha

     

    Dr. K. Ilavarasan

    Student  (MD)

    National Institute of Siddha

    Dr. M. Muthutamizhl

    Assistant Research officer

    Siddha central Research institute, CCRS, Chennai

    Dr. K. Parthasarathy

    Research officer

    Siddha central Research institute, CCRS, Chennai

     

    International Conference – 2016
    The Centre for Advanced Research in Indian System of Medicine (CARISM), SASTRA University, organized an International Conference Phytocongress 2016 - “Indian Traditional Medicine - A Conglomeration of Ancient Knowledge and Modern Science” on 21 st and 22 nd July 2016. Dr. Bhushan Patwardhan, Professor and Director of Interdisciplinary School of Health Sciences, Savitribai Phule Pune University inaugurated the conference and said “Though interactions have been taking place between modern and Indian systems of medicine, the originality is mostly forgotten and we should harness the best from each of the system for the welfare of mankind. The details of the program schedule and plenary lecture sessions of the conference are given below:
    21 July, 2016


    9.00 – 09.45 am

    Prof. Bhushan Patwardhan
    University of Pune
    Pune, India

    Inauguration

    9.45-10.30 am

    Prof. Bhushan Patwardhan
    University of Pune
    Pune, India

    Perspectives and prospective of traditional medicine:
    Phytopharmaceuticals and formulation development

    Session I - Chemical perspectives of traditional drugs

    10.30-11.15 am
    Plenary Lecture I

    Dr. Suresh Govindaraghavan
    Network Nutrition IMCD
    Australia

    Detecting adulteration in botanicals is akin to finding a needle in a haystack

    11.30 – 12.15 pm
    Plenary Lecture II

    Dr. Shrikant Anant
    University of Kansas
    Kansas City, USA

    Phytomolecules in Cancer Therapy

    12.15 - 1 .15 pm

    Paper presentations

    2.00 – 2.45 pm
    Plenary Lecture III

     Dr. Uma Maheswari Krishnan
    School of Chemical and Biotechnology, SASTRA University. Thanjavur, India

    Unraveling the mechanism of anti diabetic action of Ayurvedic preparations

    2.45 – 3.15 pm
    Plenary Lecture IV

    Prof. Mohammad Kamil
    Zayed Complex for Herbal Research,
    Abu Dhabi

    Modern sciences in the quality control of herbal medicine

    3.15 – 4.00 pm
    Plenary Lecture V

    Dr. Rajasekaran Namakkal Soorappan
    Cardiac Aging & Redox Signaling Laboratory
    University of Alabama
    Birmingham, USA

    Reductive stress cardiomyopathy and phytochemical based treatment

    4.15 – 5.15 pm

    Paper Presentations

     

    22 July, 2016


    Session II – Biochemical and biotechnological interventions in the quality control of traditional drugs

    9.00 - 9.45 am
    Plenary Lecture VI

    Prof. Intan Safinar Ismail
    Institute of Bioscience,
    University Putra
    Malaysia

    Standardization of herbal products through bioscientific approaches

    9.45 – 10.30 am
    Plenary Lecture VII

    Prof. K. Shankar Rao
    National Institute of Ayurveda
    Jaipur, Rajasthan

    Rasa Aushadhi  (Herbo-Metallic preparations) and Nanotechnology

    10.30  - 11.15 am
    Plenary Lecture VIII

    Dr. N. Angayarkanni
    Vision Research Foundation
    Sankara Nethralaya
    Chennai

    Biochemistry in the validation of Ayurvedic drugs

    11.30 – 12.15 pm
    Plenary Lecture IX

    Dr. R. Ilavarasan
    Assistant Director(S-III) In-charge
    CSMRIASDD, CCRAS,
    Arumbakkam, Chennai

    Need for the Standardization of Ayurvedic formulation

    12.15 – 1.15 pm

    Paper presentations

    Session III – Perspectives and Prospectives of Traditional drugs

    2.00 – 2.45 pm
    Plenary Lecture X

    Dr. V. Vijayakumar
    Scientific Officer (Siddha)
    Pharmacopoeial Laboratory for Indian
    Medicine, Ghaziabad

    Need for Development of Pharmacopoeial Standards with special reference to Siddha Formulations

    2.45 – 3.30 pm
    Plenary Lecture XI

    Dr. Richa Shrivastava
    Maharishi Ayurveda Products Pvt. Ltd.
    Noida- 201305, U.P.

    Contribution of modern sciences  in enhancing the quality of  Ayurvedic products

    3.30 – 4.00 pm
    Plenary Lecture XII

    Dr. L. Sivakumar
    General Manager
    SKM Siddha and Ayurveda Pvt. Ltd,
    Erode

    Siddha Industry an overview

    4.15 – 4.45 pm

    Session IV – Industry academia interactions

     

    About 194 participants that included academicians, students and research scholars from various eminent educational institutions across Tamil Nadu attended the International Conference. The participants thanked the management of SASTRA University and CARISM for organizing this conference as it provided them a golden opportunity to listen to and interact with several national and international academic giants.
    Participants from AYUSH fraternity in Phytocongress 2016

    Date Name of the Participants Student/Acadamecian Institution

    21/07/2016 & 22/07/2016

    Mr. Karunanithi Sharma

    Student

    National Institute of Ayurveda, Jaipur

    Dr. AkankshaDixlt

    Student

    National Institute of Ayurveda, Jaipur

    Mr. Shewta Paul

    Student

    National Institute of Ayurveda, Jaipur

    Dr. Omprakeshpanwar

    Student

    National Institute of Ayurveda, Jaipur

    Dr. Prasad Padekar

    Student

    National Institute of Ayurveda, Jaipur

    Dr. Amit Kumar Meena

    Student

    National Institute of Ayurveda, Jaipur

    Pradeep S. Kaushik

    Student

    Acharya Nagarjuna University, Bangalore

    Dr. Lokhan Singh Bhilala

    Student

     National Institute of Ayurveda, Jaipur

    Dr. Kamal Rathore

    Student

     National Institute of Ayurveda, Jaipur

    Dr. SuparnaShaha

    Student

    National Institute of Ayurveda, Jaipur

    Anitha John

    Research officer

    Siddha Regional Research Institute, Trivandrum

    Dr. V. Gayathri Devi

    Research officer

    Siddha Regional Research Institute, Trivandrum

    Dr. S. Selvarajan

    Research officer

    Siddha Regional Research Institute, Trivandrum

Contact

SASTRA DEEMED UNIVERSITY
Tirumalaisamudram
Thanjavur - 613401
Tamilnadu, India

+91 4362 264101 - 108
        304000 - 010
+91 4362 264120

admissions@sastra.edu

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