JRF Position in Cardiovascular Research at Vascular Biology Lab

Project Title

Effect of Fisetin in ameliorating myocardial ischemia reperfusion injury in rat model.

Funding agency

Department of Science & Technology, Government of India

Duration of Project

2018-2021

Fellowship

NET/GATE qualified or M.Tech/M.Pharm INR 25000/month

MSc: INR 18000 / month

Essential Qualification

First class in M.Pharm, M.Tech (Biotechnology or any life science stream) or MSc with experience in small animal handling is mandatory. Other skills includes molecular and cell biology techniques and good command in English is essential.

Project Description

Among all cardiovascular-related diseases, coronary artery disease remains the leading cause of death worldwide. Current therapies used to treat acute myocardial infarction are insufficient and contribute to heart damage by promoting reperfusion injury (I/R), which exacerbates cardiomyocyte death following ischemia. We have recently published that Fisetin, belongs to the flavonoid group of polyphenols are effective in attenuating myocardial ischemia reperfusion injury. However, its mode of action and the possibility to develop into a preventive nutraceutical are barely understood.

The study make use of cell lines, Langendroff perfusion apparatus and LCA ligation techniques to study the role of fisetin in the management of I/R injury.

Interested candidate may send their latest resume by email to Dr.Gino A Kurian (This email address is being protected from spambots. You need JavaScript enabled to view it.) on or before September 20, 2018. Date of interview will be notified by email later. No TA /DA will be paid for appearing in the interview.